Precision at the Point of Injury

Biomaterials that
heal, seal,
and protect.

Arogya Biotechnologies engineers next-generation biomaterials for critical unmet needs in surgery and wound care. Our first platform, HemoSeal, addresses life-threatening surgical bleeding where current sealants fall short.

ANTIBACTERIAL ELASTIC WOUND SEALING HEMORRHAGE CONTROL INJECTABLE
The Challenge

Surgical bleeding is a solved problem — except when it isn't

Uncontrolled hemorrhage remains a leading cause of preventable death across surgery, trauma, and combat medicine — not because solutions don't exist, but because every available product breaks down precisely when and where it matters most: in wet, dynamic, infected, or hard-to-reach tissue environments where reliable sealing, flexible adhesion, and infection control are simultaneously required.

$3B+
Global surgical sealant market, projected to exceed $4.6B by 2030
30%
Trauma deaths attributable to uncontrolled hemorrhage
~500K
High-risk abdominal and thoracic surgeries in the US annually
0
Currently approved antibacterial sealants for infected wound fields
  • 01
    Poor wet adhesion. Leading sealants wash away in actively bleeding fields, requiring surgeons to temporarily halt blood flow before application — a significant limitation in emergent scenarios.
  • 02
    No antibacterial activity. None of the currently approved sealants address the risk of post-operative infection at the wound site, a leading driver of surgical complications and hospital costs.
  • 03
    Mechanical mismatch. Rigid or brittle sealants fail at the interface with elastic tissues like lung, bowel, and vascular structures, leading to rebleeding and sealant detachment.
  • 04
    Limited minimally invasive access. Most sealants cannot be injected through standard laparoscopic or endoscopic ports, restricting their utility in the fastest-growing segment of surgery.
Our Solution

Introducing HemoSeal

Nature-Inspired Design
HemoSeal is inspired by biological systems that achieve strong, reliable adhesion and protection in wet and dynamic environments — from the bonding strategies of marine organisms to the body's own tissue-repair mechanisms. By drawing on these principles and combining synergistic classes of biomaterials, we engineer a material that performs where nature already knows how.
Read the Publication →

HemoSeal is a next-generation injectable hemostatic sealant that addresses the limitations of every currently available product — in a single material.

  • Strong wet-tissue adhesion — bonds reliably to actively bleeding tissue without requiring a dry operative field
  • Broad-spectrum antibacterial activity — inhibits bacterial growth without relying on antibiotics, reducing the risk of post-operative infection
  • Mechanically matched to soft tissue — elastic and flexible, conforming to dynamic anatomical structures such as lung, bowel, and vasculature
  • Injectable and minimally invasive — deliverable through standard laparoscopic or endoscopic ports for use in modern surgical workflows
  • Biodegradable and biocompatible — designed to safely resorb over time with a favorable safety profile
Technology Highlights

What makes HemoSeal different

No blood-derived materials

Fully synthetic formulation eliminates the risks of pathogen transmission, supply constraints, and immunogenic reactions associated with fibrin or thrombin-based products.

No compression required

Unlike gauze-based or pressure-dependent hemostats, HemoSeal achieves hemostasis through material adhesion alone — no manual compression needed, even in hard-to-reach anatomy.

Multi-organ applicability

Tunable mechanical properties allow HemoSeal to conform to and seal a wide range of soft tissues — including lung, liver, bowel, and vascular surfaces — without detachment under cyclic motion.

Dual hemostatic + antibacterial action

HemoSeal is the only sealant in development to combine active hemorrhage control with intrinsic broad-spectrum antibacterial protection — addressing two of surgery's most critical complications simultaneously.

Injectable through MIS ports

Syringeable formulation compatible with standard laparoscopic and endoscopic port sizes, enabling use in the fastest-growing segment of surgery where no effective injectable sealant currently exists.

Rapid on-demand gelation

Photo-activated crosslinking enables near-instantaneous gelation at the point of application — giving surgeons precise spatial and temporal control in time-critical bleeding scenarios.

Applications

Built for the highest-stakes clinical environments

General & MIS Surgery

Laparoscopic and open abdominal procedures involving the liver, spleen, bowel, and kidney — where bleeding control and infection prevention are both critical.

Thoracic & Pulmonary Surgery

Bronchoscopic and open thoracic procedures requiring a sealant that conforms to lung parenchyma, tolerates respiratory motion, and maintains adhesion in a fluid-rich environment.

Trauma Surgery

Penetrating and blunt trauma with internal hemorrhage, where speed of application, wet-field performance, and no compression requirement are decisive factors.

Military & Battlefield Medicine

Forward-deployed and combat environments where injectable, storage-stable hemostats with built-in infection control could reduce preventable casualty mortality without access to an operating room.

Emergency Medical Services

Pre-hospital bleeding control by paramedics and first responders, where ease of use and rapid gelation are essential in the critical window before hospital arrival.

Preclinical Validation

In vitro hemostasis, wet-tissue adhesion, antibacterial efficacy, and biocompatibility have been validated and published in Advanced Science (2025).

Team

Mission driven

Saumya Jain, PhD
Founder & CEO
saumya@arogyabiotechnologies.com

PhD in Chemical Engineering, UCLA. Inventor of the HemoSeal platform technology. 14 peer-reviewed publications including first-author papers in Science Translational Medicine and Advanced Science. Two filed patents. Deep expertise in hydrogel design, nanoparticle drug delivery, and tissue engineering.

Scientific & Clinical Advisors

Nasim Annabi, PhD
Scientific Advisor & PhD Supervisor · Associate Professor of Chemical Engineering, UCLA · Director, Annabi Biomaterials & Bioengineering Lab · Co-founder, GelMEDIX · Pioneer in photo-crosslinkable hydrogels for cardiovascular, pulmonary, and wound-healing applications, with over 100 peer-reviewed publications and multiple FDA-track technologies in development.
George Cheng, MD/PhD
Clinical Advisor · Interventional Pulmonologist & Assistant Professor of Medicine, UC San Diego · Co-founder, Restor3d · Specialist in bronchoscopic and minimally invasive thoracic procedures, with deep expertise in the clinical unmet needs surrounding airway and pulmonary hemorrhage — the primary target indication for HemoSeal's first-in-human study.
News & Awards

Momentum building

Jun 2026
NSF I-Corps National Program

Awarded NSF I-Corps Teams grant and selected for the National Program cohort — a competitive customer discovery initiative designed to accelerate deep-tech commercialization.

Jun 2026
Incorporated

Arogya Biotechnologies, Inc. formally incorporated in California.

May 2026
LA Best MedTech Demo Track — Won First Place Award

HemoSeal won First Place in the pitch competition at LA Best MedTech, selected from a competitive field of emerging medical device and biotechnology companies across the Los Angeles region.

Apr 2026
Taiwan Selects LA — Invited to Pitch

Selected to present HemoSeal at Taiwan Selects LA, a curated program connecting high-potential life sciences startups with international strategic partners and investors.

Mar 2026
MedTech Innovator — Invited to Pitch

Selected to pitch at MedTech Innovator, one of the most competitive medtech accelerator programs globally, with a 10% acceptance rate among applicants worldwide.

Sep 2025
Publication in Advanced Science

HemoSeal platform technology published in Advanced Science (Wiley), a high-impact peer-reviewed journal.

Get In Touch

Partner with us to stop preventable bleeding.

We are actively building relationships with strategic investors, clinical collaborators, and medtech partners who share our vision for better surgical outcomes.

Contact the Founder → Read the Publication